Human Gene SLC35E2 (uc001aia.2) Description and Page Index
  Description: Homo sapiens solute carrier family 35, member E2 (SLC35E2), transcript variant 1, mRNA.
Transcript (Including UTRs)
   Position: hg19 chr1:1,658,824-1,677,438 Size: 18,615 Total Exon Count: 6 Strand: -
Coding Region
   Position: hg19 chr1:1,663,894-1,670,996 Size: 7,103 Coding Exon Count: 5 

Page IndexSequence and LinksUniProtKB CommentsCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated: 2013-06-15

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr1:1,658,824-1,677,438)mRNA (may differ from genome)Protein (266 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSCGAP
EnsemblEntrez GeneExonPrimerGeneCardsGeneNetworkHGNC
LynxMGIneXtProtPubMedStanford SOURCETreefam
UniProtKB

-  Comments and Description Text from UniProtKB
  ID: S35E2_HUMAN
DESCRIPTION: RecName: Full=Solute carrier family 35 member E2;
FUNCTION: Putative transporter (By similarity).
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential).
SIMILARITY: Belongs to the TPT transporter family. SLC35E subfamily.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 4.63 RPKM in Brain - Cerebellum
Total median expression: 109.61 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -215.80423-0.510 Picture PostScript Text
3' UTR -2006.465070-0.396 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR000620 - DMT

Pfam Domains:
PF03151 - Triose-phosphate Transporter family

ModBase Predicted Comparative 3D Structure on P0CK97
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Descriptions from all associated GenBank mRNAs
  BC110653 - Homo sapiens similar to solute carrier family 35, member E2, mRNA (cDNA clone MGC:117254 IMAGE:4392812), complete cds.
AB209095 - Homo sapiens mRNA for cell division cycle 2-like 2 isoform 4 variant protein.
BC062371 - Homo sapiens solute carrier family 35, member E2, mRNA (cDNA clone IMAGE:3845538), partial cds.
AK092315 - Homo sapiens cDNA FLJ34996 fis, clone OCBBF2011536.
AX747477 - Sequence 1002 from Patent EP1308459.
JD059026 - Sequence 40050 from Patent EP1572962.
JD042185 - Sequence 23209 from Patent EP1572962.
AK126501 - Homo sapiens cDNA FLJ44537 fis, clone UTERU3005049.
JD260800 - Sequence 241824 from Patent EP1572962.
JD419847 - Sequence 400871 from Patent EP1572962.
JD420691 - Sequence 401715 from Patent EP1572962.
JD299959 - Sequence 280983 from Patent EP1572962.
JD538219 - Sequence 519243 from Patent EP1572962.
JD251316 - Sequence 232340 from Patent EP1572962.
JD414122 - Sequence 395146 from Patent EP1572962.
JD152073 - Sequence 133097 from Patent EP1572962.
JD419004 - Sequence 400028 from Patent EP1572962.
JD357841 - Sequence 338865 from Patent EP1572962.
JD400398 - Sequence 381422 from Patent EP1572962.
JD424503 - Sequence 405527 from Patent EP1572962.
JD526420 - Sequence 507444 from Patent EP1572962.
AK310560 - Homo sapiens cDNA, FLJ17602.
JD146816 - Sequence 127840 from Patent EP1572962.
JD262606 - Sequence 243630 from Patent EP1572962.
JD400338 - Sequence 381362 from Patent EP1572962.
JD422808 - Sequence 403832 from Patent EP1572962.
JD353554 - Sequence 334578 from Patent EP1572962.
AK309762 - Homo sapiens cDNA, FLJ99803.
JD080060 - Sequence 61084 from Patent EP1572962.
JD271192 - Sequence 252216 from Patent EP1572962.
JD062598 - Sequence 43622 from Patent EP1572962.
DQ601835 - Homo sapiens piRNA piR-39901, complete sequence.
JD496501 - Sequence 477525 from Patent EP1572962.
JD137161 - Sequence 118185 from Patent EP1572962.
JD115972 - Sequence 96996 from Patent EP1572962.
JD397665 - Sequence 378689 from Patent EP1572962.
JD086617 - Sequence 67641 from Patent EP1572962.
JD557643 - Sequence 538667 from Patent EP1572962.
JD124141 - Sequence 105165 from Patent EP1572962.
JD206471 - Sequence 187495 from Patent EP1572962.
JD195805 - Sequence 176829 from Patent EP1572962.
JD366414 - Sequence 347438 from Patent EP1572962.
JD292560 - Sequence 273584 from Patent EP1572962.
JD041533 - Sequence 22557 from Patent EP1572962.
JD169479 - Sequence 150503 from Patent EP1572962.
JD529302 - Sequence 510326 from Patent EP1572962.
JD430257 - Sequence 411281 from Patent EP1572962.
JD276535 - Sequence 257559 from Patent EP1572962.
JD096241 - Sequence 77265 from Patent EP1572962.
JD408196 - Sequence 389220 from Patent EP1572962.
JD373291 - Sequence 354315 from Patent EP1572962.
JD421526 - Sequence 402550 from Patent EP1572962.
JD257045 - Sequence 238069 from Patent EP1572962.
JD514954 - Sequence 495978 from Patent EP1572962.
JD146600 - Sequence 127624 from Patent EP1572962.
JD501999 - Sequence 483023 from Patent EP1572962.
JD412117 - Sequence 393141 from Patent EP1572962.
JD342373 - Sequence 323397 from Patent EP1572962.
JD532742 - Sequence 513766 from Patent EP1572962.
JD501238 - Sequence 482262 from Patent EP1572962.
JD098504 - Sequence 79528 from Patent EP1572962.
JD480009 - Sequence 461033 from Patent EP1572962.
JD070645 - Sequence 51669 from Patent EP1572962.
JD463269 - Sequence 444293 from Patent EP1572962.
JD535481 - Sequence 516505 from Patent EP1572962.
JD165296 - Sequence 146320 from Patent EP1572962.
JD262144 - Sequence 243168 from Patent EP1572962.
JD087137 - Sequence 68161 from Patent EP1572962.
JD367658 - Sequence 348682 from Patent EP1572962.
JD315895 - Sequence 296919 from Patent EP1572962.
JD554437 - Sequence 535461 from Patent EP1572962.
JD519702 - Sequence 500726 from Patent EP1572962.
JD093882 - Sequence 74906 from Patent EP1572962.
JD392853 - Sequence 373877 from Patent EP1572962.
JD464154 - Sequence 445178 from Patent EP1572962.
JD396289 - Sequence 377313 from Patent EP1572962.
JD342614 - Sequence 323638 from Patent EP1572962.
JD549529 - Sequence 530553 from Patent EP1572962.
JD178577 - Sequence 159601 from Patent EP1572962.
JD461155 - Sequence 442179 from Patent EP1572962.
JD521141 - Sequence 502165 from Patent EP1572962.
JD027494 - Sequence 8518 from Patent EP1572962.
JD544556 - Sequence 525580 from Patent EP1572962.
JD031381 - Sequence 12405 from Patent EP1572962.
JD108147 - Sequence 89171 from Patent EP1572962.
JD415672 - Sequence 396696 from Patent EP1572962.
JD506246 - Sequence 487270 from Patent EP1572962.
AL049665 - Human gene from PAC 283E3, chromosome 1.
JD148448 - Sequence 129472 from Patent EP1572962.
BC101666 - Homo sapiens solute carrier family 35, member E2, mRNA (cDNA clone MGC:126715 IMAGE:8069172), complete cds.
BC112289 - Homo sapiens solute carrier family 35, member E2, mRNA (cDNA clone MGC:138494 IMAGE:8327757), complete cds.
JD458754 - Sequence 439778 from Patent EP1572962.
JD476203 - Sequence 457227 from Patent EP1572962.
HQ258570 - Synthetic construct Homo sapiens clone IMAGE:100073089 solute carrier family 35, member E2 (SLC35E2) gene, encodes complete protein.
KJ892873 - Synthetic construct Homo sapiens clone ccsbBroadEn_02267 SLC35E2 gene, encodes complete protein.
JD383022 - Sequence 364046 from Patent EP1572962.
JD090174 - Sequence 71198 from Patent EP1572962.
JD498046 - Sequence 479070 from Patent EP1572962.
JD409551 - Sequence 390575 from Patent EP1572962.
JD058021 - Sequence 39045 from Patent EP1572962.
JD100866 - Sequence 81890 from Patent EP1572962.
JD247163 - Sequence 228187 from Patent EP1572962.
JD487040 - Sequence 468064 from Patent EP1572962.
JD210166 - Sequence 191190 from Patent EP1572962.
JD400167 - Sequence 381191 from Patent EP1572962.
JD565129 - Sequence 546153 from Patent EP1572962.
JD404100 - Sequence 385124 from Patent EP1572962.
JD178248 - Sequence 159272 from Patent EP1572962.
JD253454 - Sequence 234478 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: B3KWR0, NM_182838, NP_878258, O75035, P0CK97, Q2TAY8, Q569F8, Q5CZA4, Q5QPR8, Q9Y3J8, S35E2_HUMAN
UCSC ID: uc001aia.2
RefSeq Accession: NM_182838
Protein: P0CK97 (aka S35E2_HUMAN)
CCDS: CCDS33.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_182838.2
exon count: 6CDS single in 3' UTR: no RNA size: 6308
ORF size: 801CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1432.00frame shift in genome: no % Coverage: 99.78
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.