Human Gene THAP3 (uc001aod.3) Description and Page Index
  Description: Homo sapiens THAP domain containing, apoptosis associated protein 3 (THAP3), transcript variant 1, mRNA.
Transcript (Including UTRs)
   Position: hg19 chr1:6,685,210-6,693,642 Size: 8,433 Total Exon Count: 5 Strand: +
Coding Region
   Position: hg19 chr1:6,685,279-6,693,137 Size: 7,859 Coding Exon Count: 5 

Page IndexSequence and LinksGenetic AssociationsCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated: 2013-06-15

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr1:6,685,210-6,693,642)mRNA (may differ from genome)Protein (238 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
BioGPSCGAPEnsemblEntrez GeneExonPrimerGeneCards
H-INVHGNCLynxMGIOMIMPubMed
Stanford SOURCETreefamUniProtKB

-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database (archive): THAP3
CDC HuGE Published Literature: THAP3

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 8.76 RPKM in Uterus
Total median expression: 312.19 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -27.9069-0.404 Picture PostScript Text
3' UTR -219.94505-0.436 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  Pfam Domains:
PF05485 - THAP domain

ModBase Predicted Comparative 3D Structure on Q8WTV1-3
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Descriptions from all associated GenBank mRNAs
  BC092427 - Homo sapiens THAP domain containing, apoptosis associated protein 3, mRNA (cDNA clone MGC:102992 IMAGE:30376814), complete cds.
AK096217 - Homo sapiens cDNA FLJ38898 fis, clone NT2NE2000374.
BC022081 - Homo sapiens THAP domain containing, apoptosis associated protein 3, mRNA (cDNA clone IMAGE:4813302), with apparent retained intron.
DQ891670 - Synthetic construct clone IMAGE:100004300; FLH179145.01X; RZPDo839D04130D THAP domain containing, apoptosis associated protein 3 (THAP3) gene, encodes complete protein.
DQ894856 - Synthetic construct Homo sapiens clone IMAGE:100009316; FLH179141.01L; RZPDo839D04129D THAP domain containing, apoptosis associated protein 3 (THAP3) gene, encodes complete protein.
BC005114 - Homo sapiens THAP domain containing, apoptosis associated protein 3, mRNA (cDNA clone IMAGE:4053044), partial cds.
JD107794 - Sequence 88818 from Patent EP1572962.
JD341642 - Sequence 322666 from Patent EP1572962.
JD478896 - Sequence 459920 from Patent EP1572962.
JD464595 - Sequence 445619 from Patent EP1572962.
LF357477 - JP 2014500723-A/164980: Polycomb-Associated Non-Coding RNAs.
JD456080 - Sequence 437104 from Patent EP1572962.
LF357476 - JP 2014500723-A/164979: Polycomb-Associated Non-Coding RNAs.
JD531198 - Sequence 512222 from Patent EP1572962.
JD496217 - Sequence 477241 from Patent EP1572962.
MA593054 - JP 2018138019-A/164980: Polycomb-Associated Non-Coding RNAs.
MA593053 - JP 2018138019-A/164979: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: NM_001195752, NP_001182681, Q8WTV1-3
UCSC ID: uc001aod.3
RefSeq Accession: NM_001195752
Protein: Q8WTV1-3, splice isoform of Q8WTV1 CCDS: CCDS55572.1, CCDS55573.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_001195752.1
exon count: 5CDS single in 3' UTR: no RNA size: 1308
ORF size: 717CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1634.00frame shift in genome: no % Coverage: 98.70
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.