Human Gene DHRS3 (uc001aue.1) Description and Page Index
  Description: Homo sapiens dehydrogenase/reductase (SDR family) member 3 (DHRS3), mRNA.
RefSeq Summary (NM_004753): Short-chain dehydrogenases/reductases (SDRs), such as DHRS3, catalyze the oxidation/reduction of a wide range of substrates, including retinoids and steroids (Haeseleer and Palczewski, 2000 [PubMed 10800688]).[supplied by OMIM, Jun 2009]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX648476.1, SRR5189667.214862.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467144, SAMEA2467146 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000616661.5/ ENSP00000480439.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##
Transcript (Including UTRs)
   Position: hg19 chr1:12,640,551-12,656,106 Size: 15,556 Total Exon Count: 2 Strand: -


Page IndexSequence and LinksGenetic AssociationsMalaCardsCTDRNA-Seq Expression
Microarray ExpressionOther SpeciesmRNA DescriptionsPathwaysOther NamesModel Information
Methods
Data last updated: 2013-06-15

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr1:12,640,551-12,656,106)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
CGAPEnsemblExonPrimerGeneNetworkH-INVHGNC
LynxPubMedStanford SOURCEWikipedia

-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database (archive): DHRS3
CDC HuGE Published Literature: DHRS3
Positive Disease Associations: monocyte chemoattractant protein 1 (66-77)
Related Studies:
  1. monocyte chemoattractant protein 1 (66-77)
    , , . [PubMed 0]

-  MalaCards Disease Associations
  MalaCards Gene Search: DHRS3
Diseases sorted by gene-association score: neuroblastoma (2)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 75.24 RPKM in Prostate
Total median expression: 1334.64 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  KJ897985 - Synthetic construct Homo sapiens clone ccsbBroadEn_07379 DHRS3 gene, encodes complete protein.
AK225057 - Homo sapiens mRNA for dehydrogenase/reductase (SDR family) member 3 variant, clone: adSH01337.
AF061741 - Homo sapiens retinal short-chain dehydrogenase/reductase retSDR1 mRNA, complete cds.
AK222593 - Homo sapiens mRNA for dehydrogenase/reductase (SDR family) member 3 variant, clone: CAS07716.
BC002730 - Homo sapiens dehydrogenase/reductase (SDR family) member 3, mRNA (cDNA clone MGC:3784 IMAGE:3630840), complete cds.
BX648476 - Homo sapiens mRNA; cDNA DKFZp686A22160 (from clone DKFZp686A22160).
DQ893006 - Synthetic construct clone IMAGE:100005636; FLH191614.01X; RZPDo839F0277D dehydrogenase/reductase (SDR family) member 3 (DHRS3) gene, encodes complete protein.
AK312961 - Homo sapiens cDNA, FLJ93419, Homo sapiens short-chain dehydrogenase/reductase 1 (SDR1), mRNA.
DQ896252 - Synthetic construct Homo sapiens clone IMAGE:100010712; FLH191610.01L; RZPDo839F0267D dehydrogenase/reductase (SDR family) member 3 (DHRS3) gene, encodes complete protein.
CU678154 - Synthetic construct Homo sapiens gateway clone IMAGE:100018778 5' read DHRS3 mRNA.
AK310202 - Homo sapiens cDNA, FLJ17244.
AY358093 - Homo sapiens clone DNA49828 SDR1 (UNQ2424) mRNA, complete cds.
DQ426870 - Homo sapiens dehydrogenase/reductase member 3 (DHRS3) mRNA, partial cds, alternatively spliced.
DQ426869 - Homo sapiens dehydrogenase/reductase member 3 (DHRS3) mRNA, partial cds, alternatively spliced.
AK309282 - Homo sapiens cDNA, FLJ99323.

-  Biochemical and Signaling Pathways
  KEGG - Kyoto Encyclopedia of Genes and Genomes
hsa00830 - Retinol metabolism
hsa01100 - Metabolic pathways

-  Other Names for This Gene
  Alternate Gene Symbols: DQ426870
UCSC ID: uc001aue.1
RefSeq Accession: NM_004753

-  Gene Model Information
 
category: nearCoding nonsense-mediated-decay: no RNA accession: DQ426870.1
exon count: 2CDS single in 3' UTR: no RNA size: 151
ORF size: 0CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 290.00frame shift in genome: no % Coverage: 100.00
has start codon: no stop codon in genome: no # of Alignments: 1
has end codon: no retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.