Human Gene ANKRD34A (uc001enq.1) Description and Page Index
  Description: Homo sapiens ankyrin repeat domain 34A (ANKRD34A), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr1:145,470,508-145,475,647 Size: 5,140 Total Exon Count: 4 Strand: +
Coding Region
   Position: hg19 chr1:145,473,329-145,474,819 Size: 1,491 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsCTDGene AllelesMicroarray Expression
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Data last updated: 2013-06-15

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr1:145,470,508-145,475,647)mRNA (may differ from genome)Protein (496 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsGeneNetwork
PubMedStanford SOURCETreefamUniProtKB

-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=Ankyrin repeat domain-containing protein 34A;
SIMILARITY: Belongs to the ANKRD34 family.
SIMILARITY: Contains 4 ANK repeats.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
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+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -501.301293-0.388 Picture PostScript Text
3' UTR -260.80828-0.315 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR002110 - Ankyrin_rpt
IPR020683 - Ankyrin_rpt-contain_dom

Pfam Domains:
PF00023 - Ankyrin repeat
PF12796 - Ankyrin repeats (3 copies)
PF13606 - Ankyrin repeat
PF13637 - Ankyrin repeats (many copies)
PF13857 - Ankyrin repeats (many copies)

SCOP Domains:
48403 - Ankyrin repeat

ModBase Predicted Comparative 3D Structure on Q69YU3
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 Protein Sequence    

-  Descriptions from all associated GenBank mRNAs
  AK128050 - Homo sapiens cDNA FLJ46170 fis, clone TESTI4003404, highly similar to Homo sapiens ankyrin repeat domain 34A (ANKRD34A), mRNA.
AK094282 - Homo sapiens cDNA FLJ36963 fis, clone BRACE2006055, highly similar to Homo sapiens ankyrin repeat domain 34A (ANKRD34A), mRNA.
JD256923 - Sequence 237947 from Patent EP1572962.
JD213733 - Sequence 194757 from Patent EP1572962.
JD257465 - Sequence 238489 from Patent EP1572962.
JD146447 - Sequence 127471 from Patent EP1572962.
JD488056 - Sequence 469080 from Patent EP1572962.
AB464458 - Synthetic construct DNA, clone: pF1KB8843, Homo sapiens ANKRD34 gene for ankyrin repeat domain 34A, without stop codon, in Flexi system.
AL359622 - Homo sapiens mRNA; cDNA DKFZp761F202 (from clone DKFZp761F202).
JD140894 - Sequence 121918 from Patent EP1572962.
JD540809 - Sequence 521833 from Patent EP1572962.
JD495779 - Sequence 476803 from Patent EP1572962.
JD050789 - Sequence 31813 from Patent EP1572962.
JD049106 - Sequence 30130 from Patent EP1572962.
JD098218 - Sequence 79242 from Patent EP1572962.
JD197347 - Sequence 178371 from Patent EP1572962.
JD214389 - Sequence 195413 from Patent EP1572962.
JD520257 - Sequence 501281 from Patent EP1572962.
JD494565 - Sequence 475589 from Patent EP1572962.
JD432007 - Sequence 413031 from Patent EP1572962.
JD076109 - Sequence 57133 from Patent EP1572962.
JD521391 - Sequence 502415 from Patent EP1572962.
JD544456 - Sequence 525480 from Patent EP1572962.
JD134692 - Sequence 115716 from Patent EP1572962.
JD516050 - Sequence 497074 from Patent EP1572962.
JD095778 - Sequence 76802 from Patent EP1572962.
JD039300 - Sequence 20324 from Patent EP1572962.
JD092980 - Sequence 74004 from Patent EP1572962.
JD111921 - Sequence 92945 from Patent EP1572962.
JD440080 - Sequence 421104 from Patent EP1572962.
JD328280 - Sequence 309304 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: AN34A_HUMAN, ANKRD34, B3KSU3, NM_001039888, NP_001034977, Q69YU3
UCSC ID: uc001enq.1
RefSeq Accession: NM_001039888
Protein: Q69YU3 (aka AN34A_HUMAN)

-  Gene Model Information
category: coding nonsense-mediated-decay: no RNA accession: NM_001039888.2
exon count: 4CDS single in 3' UTR: no RNA size: 3612
ORF size: 1491CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1390.50frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.