Human Gene FAM89A (uc001hui.2) Description and Page Index
  Description: Homo sapiens family with sequence similarity 89, member A (FAM89A), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr1:231,154,704-231,175,995 Size: 21,292 Total Exon Count: 2 Strand: -
Coding Region
   Position: hg19 chr1:231,155,609-231,175,957 Size: 20,349 Coding Exon Count: 2 

Page IndexSequence and LinksUniProtKB CommentsGenetic AssociationsCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA Descriptions
Other NamesModel InformationMethods
Data last updated: 2013-06-15

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr1:231,154,704-231,175,995)mRNA (may differ from genome)Protein (184 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSCGAP
EnsemblEntrez GeneExonPrimerGeneCardsGeneNetworkH-INV
HGNCHPRDLynxMGIneXtProtPubMed
Stanford SOURCETreefamUniProtKB

-  Comments and Description Text from UniProtKB
  ID: FA89A_HUMAN
DESCRIPTION: RecName: Full=Protein FAM89A;
SIMILARITY: Belongs to the FAM89 family.

-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database (archive): FAM89A
CDC HuGE Published Literature: FAM89A
Positive Disease Associations: Leprosy
Related Studies:
  1. Leprosy
    , , . [PubMed 0]

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 22.39 RPKM in Adipose - Visceral (Omentum)
Total median expression: 235.24 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -18.2038-0.479 Picture PostScript Text
3' UTR -256.44905-0.283 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR026654 - FAM89

ModBase Predicted Comparative 3D Structure on Q96GI7
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserGenome BrowserNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGDEnsembl   
 Protein SequenceProtein Sequence   
 AlignmentAlignment   

-  Descriptions from all associated GenBank mRNAs
  BC009447 - Homo sapiens family with sequence similarity 89, member A, mRNA (cDNA clone MGC:15887 IMAGE:3530481), complete cds.
HZ043350 - JP 2015510401-A/440: MESENCHYMAL STEM CELLS FOR IN VITRO MODELING AND CELL-BASED THERAPY OF HUMAN DISEASES AND BANKS THEREOF.
HZ081976 - JP 2015514392-A/440: MicroRNAS FOR THE GENERATION OF ASTROCYTES.
HZ408806 - JP 2015528002-A/1403: CHIRAL CONTROL.
LF404447 - JP 2015509366-A/440: GENERATION OF NEURAL STEM CELLS AND MOTOR NEURONS.
LG052140 - KR 1020150036642-A/1406: CHIRAL CONTROL.
MA353978 - JP 2018075017-A/440: GENERATION OF NEURAL STEM CELLS AND MOTOR NEURONS.
HI965578 - Sequence 863 from Patent WO2010139812.
HI966022 - Sequence 342 from Patent WO2010139811.
HI966888 - Sequence 342 from Patent WO2010139810.
HV594754 - JP 2010539959-A/135: Micromirs.
HW413637 - WO 2014003053-A/86: Method for screening pancreatic cancer and test kit therefor.
HW799106 - WO 2014192907-A/212: Method for detecting miRNA used for differentiating disorders causing motor neuropathy.
HW824052 - JP 2015502176-A/113: Methods and Kits for Detecting Subjects at Risk of Having Cancer.
HZ043316 - JP 2015510401-A/406: MESENCHYMAL STEM CELLS FOR IN VITRO MODELING AND CELL-BASED THERAPY OF HUMAN DISEASES AND BANKS THEREOF.
HZ074643 - JP 2013535982-A/734: Single-Stranded RNAi Agents Containing an Internal, Non-Nucleic Acid Spacer.
HZ081942 - JP 2015514392-A/406: MicroRNAS FOR THE GENERATION OF ASTROCYTES.
HZ157311 - JP 2015130862-A/135: Micromirs.
HZ479633 - JP 2015535430-A/139: TERMINALLY MODIFIED RNA.
HZ789564 - JP 2016504050-A/1309: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
JA401616 - Sequence 863 from Patent WO2011080318.
JA402594 - Sequence 863 from Patent WO2011080315.
JA403601 - Sequence 863 from Patent WO2011080316.
JA406232 - Sequence 863 from Patent EP2336353.
JA427121 - Sequence 454 from Patent WO2011072177.
JA429758 - Sequence 863 from Patent WO2011095623.
JB620828 - Sequence 808 from Patent WO2013063544.
JC512296 - Sequence 2549 from Patent WO2014113089.
LF161298 - JP 2016513950-A/1364: Oligomers with improved off-target profile.
LF404413 - JP 2015509366-A/406: GENERATION OF NEURAL STEM CELLS AND MOTOR NEURONS.
LP726648 - Sequence 342 from Patent EP2883966.
LP818918 - Sequence 342 from Patent EP3296406.
LP938860 - Sequence 342 from Patent EP3184651.
LQ069884 - Sequence 208 from Patent EP2964234.
LY404819 - KR 1020160117535-A/124: POLY OLIGOMER COMPOUND WITH BIOCLEAVABLE CONJUGATES.
MA260058 - JP 2017505623-A/124: POLY OLIGOMER COMPOUND WITH BIOCLEAVABLE CONJUGATES.
MA353944 - JP 2018075017-A/406: GENERATION OF NEURAL STEM CELLS AND MOTOR NEURONS.
MS834717 - Sequence 863 from Patent EP3112479.
MA643385 - JP 2017113010-A/1309: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
MA731269 - JP 2017140048-A/139: TERMINALLY MODIFIED RNA.
LQ970703 - Sequence 113 from Patent EP2800820.
MA405869 - WO 2018155427-A/643: A probe with reduced false positive binding, a method to desing the probe, and the use thereof.
MP045618 - Sequence 440 from Patent EP3401394.
MP084288 - Sequence 440 from Patent EP3401393.
MP045584 - Sequence 406 from Patent EP3401394.
MP084254 - Sequence 406 from Patent EP3401393.
MA800438 - JP 2018183181-A/1309: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.

-  Other Names for This Gene
  Alternate Gene Symbols: C1orf153, FA89A_HUMAN, NM_198552, NP_940954, Q96GI7
UCSC ID: uc001hui.2
RefSeq Accession: NM_198552
Protein: Q96GI7 (aka FA89A_HUMAN)
CCDS: CCDS1590.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_198552.2
exon count: 2CDS single in 3' UTR: no RNA size: 1516
ORF size: 555CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1310.00frame shift in genome: no % Coverage: 98.81
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.