Human Gene CCNJ (uc001klm.3) Description and Page Index
  Description: Homo sapiens cyclin J (CCNJ), transcript variant 2, mRNA.
Transcript (Including UTRs)
   Position: hg19 chr10:97,803,159-97,820,625 Size: 17,467 Total Exon Count: 6 Strand: +
Coding Region
   Position: hg19 chr10:97,804,151-97,817,998 Size: 13,848 Coding Exon Count: 5 

Page IndexSequence and LinksUniProtKB CommentsCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated: 2013-06-15

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr10:97,803,159-97,820,625)mRNA (may differ from genome)Protein (372 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
BioGPSCGAPEnsemblEntrez GeneExonPrimerGeneCards
GeneNetworkH-INVHGNCLynxMGIneXtProt
PubMedStanford SOURCETreefamUniProtKB

-  Comments and Description Text from UniProtKB
  ID: CCNJ_HUMAN
DESCRIPTION: RecName: Full=Cyclin-J;
SIMILARITY: Belongs to the cyclin family.
SIMILARITY: Contains 1 cyclin N-terminal domain.
SEQUENCE CAUTION: Sequence=BAA91887.1; Type=Erroneous initiation;

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 3.84 RPKM in Spleen
Total median expression: 92.50 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -205.20359-0.572 Picture PostScript Text
3' UTR -672.892627-0.256 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR013763 - Cyclin-like
IPR004367 - Cyclin_C
IPR006671 - Cyclin_N

Pfam Domains:
PF00134 - Cyclin, N-terminal domain
PF02984 - Cyclin, C-terminal domain

SCOP Domains:
47954 - Cyclin-like

ModBase Predicted Comparative 3D Structure on Q5T5M9
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0005634 nucleus


-  Descriptions from all associated GenBank mRNAs
  BC043175 - Homo sapiens cyclin J, mRNA (cDNA clone MGC:44167 IMAGE:5287365), complete cds.
AK297264 - Homo sapiens cDNA FLJ58102 complete cds, highly similar to Homo sapiens cyclin J (CCNJ), mRNA.
AK092360 - Homo sapiens cDNA FLJ35041 fis, clone OCBBF2017458, highly similar to Homo sapiens cyclin J (CCNJ), mRNA.
AX747499 - Sequence 1024 from Patent EP1308459.
CU692146 - Synthetic construct Homo sapiens gateway clone IMAGE:100020930 5' read CCNJ mRNA.
HQ448507 - Synthetic construct Homo sapiens clone IMAGE:100071940; CCSB010549_01 cyclin J (CCNJ) gene, encodes complete protein.
KJ894049 - Synthetic construct Homo sapiens clone ccsbBroadEn_03443 CCNJ gene, encodes complete protein.
AK001757 - Homo sapiens cDNA FLJ10895 fis, clone NT2RP4002905.
AK303018 - Homo sapiens cDNA FLJ54948 complete cds, highly similar to Homo sapiens cyclin J (CCNJ), mRNA.
JD263627 - Sequence 244651 from Patent EP1572962.
JD308447 - Sequence 289471 from Patent EP1572962.
JD345181 - Sequence 326205 from Patent EP1572962.
JD049290 - Sequence 30314 from Patent EP1572962.
AK025932 - Homo sapiens cDNA: FLJ22279 fis, clone HRC03831.
JD537651 - Sequence 518675 from Patent EP1572962.
JD174834 - Sequence 155858 from Patent EP1572962.
JD497232 - Sequence 478256 from Patent EP1572962.
JD186769 - Sequence 167793 from Patent EP1572962.
JD562862 - Sequence 543886 from Patent EP1572962.
JD067173 - Sequence 48197 from Patent EP1572962.
JD469395 - Sequence 450419 from Patent EP1572962.
JD167143 - Sequence 148167 from Patent EP1572962.
JD147784 - Sequence 128808 from Patent EP1572962.
JD566109 - Sequence 547133 from Patent EP1572962.
JD496894 - Sequence 477918 from Patent EP1572962.
JD348917 - Sequence 329941 from Patent EP1572962.
JD236597 - Sequence 217621 from Patent EP1572962.
JD433079 - Sequence 414103 from Patent EP1572962.
JD439279 - Sequence 420303 from Patent EP1572962.
JD303424 - Sequence 284448 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: B7Z4E7, CCNJ_HUMAN, NM_019084, NP_061957, Q5T5M9, Q86XL1, Q9NV69
UCSC ID: uc001klm.3
RefSeq Accession: NM_019084
Protein: Q5T5M9 (aka CCNJ_HUMAN)
CCDS: CCDS7445.1, CCDS44462.1, CCDS44463.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_019084.4
exon count: 6CDS single in 3' UTR: no RNA size: 4120
ORF size: 1119CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 2064.50frame shift in genome: no % Coverage: 99.64
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.