Human Gene GABARAPL1 (uc001qxt.3) Description and Page Index
  Description: Homo sapiens GABA(A) receptor-associated protein like 1 (GABARAPL1), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr12:10,365,489-10,375,724 Size: 10,236 Total Exon Count: 6 Strand: +


Page IndexSequence and LinksGenetic AssociationsMalaCardsCTDRNA-Seq Expression
Microarray ExpressionOther SpeciesmRNA DescriptionsPathwaysOther NamesModel Information
Methods
Data last updated: 2013-06-15

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr12:10,365,489-10,375,724)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
BioGPSCGAPEnsemblExonPrimerGeneNetworkH-INV
HGNCHuman Cortex Gene ExpressionLynxPubMedStanford SOURCE

-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database (archive): GABARAPL1
CDC HuGE Published Literature: GABARAPL1
Positive Disease Associations: Body Height , Respiratory Function Tests
Related Studies:
  1. Body Height
    Caroline S Fox et al. BMC medical genetics 2007, Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project., BMC medical genetics. [PubMed 17903300]
    Adiposity traits are associated with SNPs on the Affymetrix 100K SNP GeneChip. Replication of these initial findings is necessary. These data will serve as a resource for replication as more genes become identified with BMI and WC.
  2. Respiratory Function Tests
    Jemma B Wilk et al. BMC medical genetics 2007, Framingham Heart Study genome-wide association: results for pulmonary function measures., BMC medical genetics. [PubMed 17903307]
    GSTO2 and IL6R are credible candidate genes for association to pulmonary function identified by GWA. These and other observed associations warrant replication studies. This resource of GWA results for pulmonary function measures is publicly available at http://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?id=phs000007 webcite.

-  MalaCards Disease Associations
  MalaCards Gene Search: GABARAPL1
Diseases sorted by gene-association score: amyotrophic lateral sclerosis type 14 (2), retinitis pigmentosa (0)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 111.04 RPKM in Brain - Frontal Cortex (BA9)
Total median expression: 2360.28 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  LF207423 - JP 2014500723-A/14926: Polycomb-Associated Non-Coding RNAs.
AF287012 - Homo sapiens early estrogen-regulated protein (GEC1) mRNA, complete cds.
LF207424 - JP 2014500723-A/14927: Polycomb-Associated Non-Coding RNAs.
AF087847 - Homo sapiens GABA-A receptor-associated protein like 1 (GABARAPL1) mRNA, complete cds.
AK303581 - Homo sapiens cDNA FLJ59143 complete cds, highly similar to Gamma-aminobutyric acid receptor-associated protein-like 1.
AK315418 - Homo sapiens cDNA, FLJ96471, highly similar to Homo sapiens GABA(A) receptor-associated protein like 1(GABARAPL1), mRNA.
AK074195 - Homo sapiens cDNA FLJ23615 fis, clone ADKA03291, highly similar to Homo sapiens GABA-A receptor-associated protein mRNA.
BC028315 - Homo sapiens GABA(A) receptor-associated protein like 1, mRNA (cDNA clone MGC:35365 IMAGE:5183078), complete cds.
BC009309 - Homo sapiens GABA(A) receptor-associated protein like 1, mRNA (cDNA clone MGC:16572 IMAGE:4100219), complete cds.
JD310283 - Sequence 291307 from Patent EP1572962.
AL136676 - Homo sapiens mRNA; cDNA DKFZp564N1272 (from clone DKFZp564N1272).
LF366077 - JP 2014500723-A/173580: Polycomb-Associated Non-Coding RNAs.
JN663881 - Homo sapiens GABARAPL1-a (GABARAPL1) mRNA, complete cds, alternatively spliced.
BX648781 - Homo sapiens mRNA; cDNA DKFZp686D21148 (from clone DKFZp686D21148).
BC008891 - Homo sapiens cDNA clone IMAGE:3836311, containing frame-shift errors.
JD058497 - Sequence 39521 from Patent EP1572962.
JD407818 - Sequence 388842 from Patent EP1572962.
AM393185 - Synthetic construct Homo sapiens clone IMAGE:100001882 for hypothetical protein (GABARAPL1 gene).
AM393189 - Synthetic construct Homo sapiens clone IMAGE:100001887 for hypothetical protein (GABARAPL1 gene).
AB463662 - Synthetic construct DNA, clone: pF1KB8105, Homo sapiens GABARAPL1 gene for GABA(A) receptor-associated protein like 1, without stop codon, in Flexi system.
DQ893103 - Synthetic construct clone IMAGE:100005733; FLH193766.01X; RZPDo839B1079D GABA(A) receptor-associated protein like 1 (GABARAPL1) gene, encodes complete protein.
DQ896375 - Synthetic construct Homo sapiens clone IMAGE:100010835; FLH193762.01L; RZPDo839B1069D GABA(A) receptor-associated protein like 1 (GABARAPL1) gene, encodes complete protein.
KJ893440 - Synthetic construct Homo sapiens clone ccsbBroadEn_02834 GABARAPL1 gene, encodes complete protein.
CR533480 - Homo sapiens full open reading frame cDNA clone RZPDo834A0917D for gene GABARAPL1, GABA(A) receptor-associated protein like 1; complete cds, incl. stopcodon.
LF366078 - JP 2014500723-A/173581: Polycomb-Associated Non-Coding RNAs.
AK056846 - Homo sapiens cDNA FLJ32284 fis, clone PROST2000241, moderately similar to GABA(A) receptor-associated protein.
AK092075 - Homo sapiens cDNA FLJ34756 fis, clone NT2NE2001655.
LF366082 - JP 2014500723-A/173585: Polycomb-Associated Non-Coding RNAs.
AK124150 - Homo sapiens cDNA FLJ42156 fis, clone THYMU2003907.
JD449092 - Sequence 430116 from Patent EP1572962.
JD436866 - Sequence 417890 from Patent EP1572962.
JD540073 - Sequence 521097 from Patent EP1572962.
LF366084 - JP 2014500723-A/173587: Polycomb-Associated Non-Coding RNAs.
JD102805 - Sequence 83829 from Patent EP1572962.
JD043061 - Sequence 24085 from Patent EP1572962.
JD376543 - Sequence 357567 from Patent EP1572962.
JD504648 - Sequence 485672 from Patent EP1572962.
LF366085 - JP 2014500723-A/173588: Polycomb-Associated Non-Coding RNAs.
JD555586 - Sequence 536610 from Patent EP1572962.
JD434856 - Sequence 415880 from Patent EP1572962.
JD358109 - Sequence 339133 from Patent EP1572962.
JD235231 - Sequence 216255 from Patent EP1572962.
JD222494 - Sequence 203518 from Patent EP1572962.
JD383080 - Sequence 364104 from Patent EP1572962.
JD373912 - Sequence 354936 from Patent EP1572962.
JD519921 - Sequence 500945 from Patent EP1572962.
JD393671 - Sequence 374695 from Patent EP1572962.
JD430028 - Sequence 411052 from Patent EP1572962.
JD320782 - Sequence 301806 from Patent EP1572962.
JD229172 - Sequence 210196 from Patent EP1572962.
JD227995 - Sequence 209019 from Patent EP1572962.
JD429775 - Sequence 410799 from Patent EP1572962.
JD261900 - Sequence 242924 from Patent EP1572962.
JD431810 - Sequence 412834 from Patent EP1572962.
JD547305 - Sequence 528329 from Patent EP1572962.
JD107743 - Sequence 88767 from Patent EP1572962.
JD049060 - Sequence 30084 from Patent EP1572962.
JD088748 - Sequence 69772 from Patent EP1572962.
JD423441 - Sequence 404465 from Patent EP1572962.
JD540963 - Sequence 521987 from Patent EP1572962.
JD359644 - Sequence 340668 from Patent EP1572962.
JD218930 - Sequence 199954 from Patent EP1572962.
LF366086 - JP 2014500723-A/173589: Polycomb-Associated Non-Coding RNAs.
JD483588 - Sequence 464612 from Patent EP1572962.
MA601654 - JP 2018138019-A/173580: Polycomb-Associated Non-Coding RNAs.
MA601655 - JP 2018138019-A/173581: Polycomb-Associated Non-Coding RNAs.
MA601659 - JP 2018138019-A/173585: Polycomb-Associated Non-Coding RNAs.
MA601661 - JP 2018138019-A/173587: Polycomb-Associated Non-Coding RNAs.
MA601662 - JP 2018138019-A/173588: Polycomb-Associated Non-Coding RNAs.
MA601663 - JP 2018138019-A/173589: Polycomb-Associated Non-Coding RNAs.
MA443000 - JP 2018138019-A/14926: Polycomb-Associated Non-Coding RNAs.
MA443001 - JP 2018138019-A/14927: Polycomb-Associated Non-Coding RNAs.

-  Biochemical and Signaling Pathways
  KEGG - Kyoto Encyclopedia of Genes and Genomes
hsa04140 - Regulation of autophagy

-  Other Names for This Gene
  Alternate Gene Symbols: AK056846
UCSC ID: uc001qxt.3
RefSeq Accession: NM_031412

-  Gene Model Information
 
category: nearCoding nonsense-mediated-decay: no RNA accession: AK056846.1
exon count: 6CDS single in 3' UTR: no RNA size: 2026
ORF size: 0CDS single in intron: no Alignment % ID: 99.80
txCdsPredict score: 266.50frame shift in genome: no % Coverage: 100.00
has start codon: no stop codon in genome: no # of Alignments: 1
has end codon: no retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.