Human Gene NR2F2 (uc002btp.3) Description and Page Index
Description: Homo sapiens nuclear receptor subfamily 2, group F, member 2 (NR2F2), transcript variant 2, mRNA. RefSeq Summary (NM_001145155): This gene encodes a member of the steroid thyroid hormone superfamily of nuclear receptors. The encoded protein is a ligand inducible transcription factor that is involved in the regulation of many different genes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]. Transcript (Including UTRs) Position: hg19 chr15:96,869,157-96,883,492 Size: 14,336 Total Exon Count: 3 Strand: + Coding Region Position: hg19 chr15:96,869,539-96,880,851 Size: 11,313 Coding Exon Count: 3
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF00104 - Ligand-binding domain of nuclear hormone receptor
ModBase Predicted Comparative 3D Structure on P24468-2
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.