Human Gene ZNF321P (uc002qaj.1) Description and Page Index
  Description: Homo sapiens zinc finger protein 321, pseudogene (ZNF321P), non-coding RNA.
RefSeq Summary (NM_001202473): This locus represents naturally occurring read-through transcription between the zinc finger protein 816 (ZNF816) gene and the zinc finger protein 321 (ZNF321) pseudogene on chromosome 19. The read-through transcript encodes a KRAB domain-containing protein that shares sequence identity with the upstream gene product, but it contains a distinct C-terminus encoded by exon structure from the downstream pseudogene. [provided by RefSeq, Jan 2011]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: DB207639.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## readthrough transcript :: includes exons from GeneID 125893, 399669 ##RefSeq-Attributes-END##
Transcript (Including UTRs)
   Position: hg19 chr19:53,430,388-53,445,847 Size: 15,460 Total Exon Count: 2 Strand: -
Coding Region
   Position: hg19 chr19:53,432,156-53,432,647 Size: 492 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsGene AllelesRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated: 2013-06-15

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr19:53,430,388-53,445,847)mRNA (may differ from genome)Protein (163 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsH-INV
HGNCHPRDLynxMGIneXtProtPubMed
Stanford SOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: ZN321_HUMAN
DESCRIPTION: RecName: Full=Putative protein ZNF321; AltName: Full=Zinc finger protein 321 pseudogene;
CAUTION: Could be the product of a pseudogene.
CAUTION: Despite its name, it does not contain a zinc-finger domain.
SEQUENCE CAUTION: Sequence=BAH14874.1; Type=Erroneous translation; Note=Wrong choice of CDS; Sequence=BAH14874.1; Type=Miscellaneous discrepancy; Note=Readthrough transcript ZNF816-ZNF321; Sequence=CAH18080.1; Type=Erroneous translation; Note=Wrong choice of CDS; Sequence=CAH18080.1; Type=Miscellaneous discrepancy; Note=Readthrough transcript ZNF816-ZNF321;

+  Common Gene Haplotype Alleles
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-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 5.25 RPKM in Bladder
Total median expression: 91.55 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -25.0074-0.338 Picture PostScript Text
3' UTR -765.631768-0.433 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q8N8H1
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  CR749224 - Homo sapiens mRNA; cDNA DKFZp781C2298 (from clone DKFZp781C2298).
BC046449 - Homo sapiens zinc finger protein 321, mRNA (cDNA clone MGC:35402 IMAGE:5186884), complete cds.
AK096828 - Homo sapiens cDNA FLJ39509 fis, clone PROST2017836.
JD171143 - Sequence 152167 from Patent EP1572962.
JD481875 - Sequence 462899 from Patent EP1572962.
JD395897 - Sequence 376921 from Patent EP1572962.
JD520686 - Sequence 501710 from Patent EP1572962.
JD086285 - Sequence 67309 from Patent EP1572962.
JD447982 - Sequence 429006 from Patent EP1572962.
JD267513 - Sequence 248537 from Patent EP1572962.
JD291997 - Sequence 273021 from Patent EP1572962.
JD431331 - Sequence 412355 from Patent EP1572962.
JD136370 - Sequence 117394 from Patent EP1572962.
JD100577 - Sequence 81601 from Patent EP1572962.
JD473879 - Sequence 454903 from Patent EP1572962.
JD452293 - Sequence 433317 from Patent EP1572962.
JD483022 - Sequence 464046 from Patent EP1572962.
JD136369 - Sequence 117393 from Patent EP1572962.
JD136368 - Sequence 117392 from Patent EP1572962.
JD228383 - Sequence 209407 from Patent EP1572962.
JD208862 - Sequence 189886 from Patent EP1572962.
JD159049 - Sequence 140073 from Patent EP1572962.
JD286388 - Sequence 267412 from Patent EP1572962.
JD499205 - Sequence 480229 from Patent EP1572962.
JD291736 - Sequence 272760 from Patent EP1572962.
JD505221 - Sequence 486245 from Patent EP1572962.
JD203943 - Sequence 184967 from Patent EP1572962.
JD072103 - Sequence 53127 from Patent EP1572962.
JD397566 - Sequence 378590 from Patent EP1572962.
JD070073 - Sequence 51097 from Patent EP1572962.
JD338084 - Sequence 319108 from Patent EP1572962.
JD522944 - Sequence 503968 from Patent EP1572962.
JD153219 - Sequence 134243 from Patent EP1572962.
JD198443 - Sequence 179467 from Patent EP1572962.
JD506096 - Sequence 487120 from Patent EP1572962.
JD563109 - Sequence 544133 from Patent EP1572962.
JD427127 - Sequence 408151 from Patent EP1572962.
JD342364 - Sequence 323388 from Patent EP1572962.
JD219131 - Sequence 200155 from Patent EP1572962.
JD205328 - Sequence 186352 from Patent EP1572962.
JD243644 - Sequence 224668 from Patent EP1572962.
JD093540 - Sequence 74564 from Patent EP1572962.
JD364401 - Sequence 345425 from Patent EP1572962.
JD550575 - Sequence 531599 from Patent EP1572962.
JD560996 - Sequence 542020 from Patent EP1572962.
JD165287 - Sequence 146311 from Patent EP1572962.
JD087128 - Sequence 68152 from Patent EP1572962.
JD247471 - Sequence 228495 from Patent EP1572962.
JD558431 - Sequence 539455 from Patent EP1572962.
BC119627 - Homo sapiens zinc finger protein 321, mRNA (cDNA clone MGC:149471 IMAGE:40115508), complete cds.
BC119628 - Homo sapiens zinc finger protein 321, mRNA (cDNA clone MGC:149472 IMAGE:40115510), complete cds.
JD297162 - Sequence 278186 from Patent EP1572962.
JD297163 - Sequence 278187 from Patent EP1572962.
JD330624 - Sequence 311648 from Patent EP1572962.
AK316503 - Homo sapiens cDNA, FLJ79402 complete cds, highly similar to Zinc finger protein 611.
JD274491 - Sequence 255515 from Patent EP1572962.
JD516148 - Sequence 497172 from Patent EP1572962.
JD357710 - Sequence 338734 from Patent EP1572962.
JD357709 - Sequence 338733 from Patent EP1572962.
JD314851 - Sequence 295875 from Patent EP1572962.
KJ904273 - Synthetic construct Homo sapiens clone ccsbBroadEn_13667 ZNF321P gene, encodes complete protein.
KJ896235 - Synthetic construct Homo sapiens clone ccsbBroadEn_05629 ZNF321P gene, encodes complete protein.
JD535268 - Sequence 516292 from Patent EP1572962.
JD250861 - Sequence 231885 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: B7ZB38, NM_001202473, NP_001189402, NR_037805, Q68DZ0, Q86SS5, Q8N8H1, ZN321_HUMAN, ZNF321
UCSC ID: uc002qaj.1
RefSeq Accession: NM_001202473
Protein: Q8N8H1 (aka ZN321_HUMAN)

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NR_037805.1
exon count: 2CDS single in 3' UTR: no RNA size: 2334
ORF size: 492CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 688.50frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.