Human Gene TACC1 (uc003xmd.1) Description and Page Index
Description: Homo sapiens transforming, acidic coiled-coil containing protein 1 (TACC1), transcript variant 2, mRNA. RefSeq Summary (NM_001122824): This locus may represent a breast cancer candidate gene. It is located close to FGFR1 on a region of chromosome 8 that is amplified in some breast cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY177411.1, SRR1803616.12304.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## Transcript (Including UTRs) Position: hg19 chr8:38,614,757-38,688,695 Size: 73,939 Total Exon Count: 4 Strand: + Coding Region Position: hg19 chr8:38,614,851-38,688,695 Size: 73,845 Coding Exon Count: 4
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.