Human Gene RPS6KC1 (uc009xdi.1) Description and Page Index
  Description: Homo sapiens ribosomal protein S6 kinase, 52kDa, polypeptide 1 (RPS6KC1), transcript variant 1, mRNA.
RefSeq Summary (NM_012424): Sphingosine kinase catalyzes the formation of sphingosine 1 phosphate, a lipid cellular messenger. The protein encoded by this gene can bind to sphingosine kinase and to phosphatidylinositol 3-phosphate, suggesting a role in sphingosine 1 phophate signaling. The encoded protein can also bind to peroxiredoxin-3 and may help transport it to mitochondria. [provided by RefSeq, Mar 2017].
Transcript (Including UTRs)
   Position: hg19 chr1:213,234,724-213,244,383 Size: 9,660 Total Exon Count: 2 Strand: +

Page IndexSequence and LinksCTDRNA-Seq ExpressionMicroarray ExpressionOther Species
mRNA DescriptionsOther NamesModel InformationMethods
Data last updated: 2013-06-15

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr1:213,234,724-213,244,383)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
LynxPubMedStanford SOURCEWikipedia

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 11.16 RPKM in Testis
Total median expression: 237.70 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog

-  Descriptions from all associated GenBank mRNAs
  AK122989 - Homo sapiens cDNA FLJ16747 fis, clone FCBBF3008159, highly similar to Ribosomal protein S6 kinase delta-1 (EC
AK299298 - Homo sapiens cDNA FLJ50840 complete cds, highly similar to Ribosomal protein S6 kinase delta-1 (EC
AF477978 - Homo sapiens RSK-like protein (RPK118) mRNA, complete cds.
BC104769 - Homo sapiens ribosomal protein S6 kinase, 52kDa, polypeptide 1, mRNA (cDNA clone MGC:132429 IMAGE:8143772), complete cds.
BC143449 - Homo sapiens cDNA clone IMAGE:9051957, with apparent retained intron.
BC143473 - Homo sapiens cDNA clone IMAGE:9051981.
BC143474 - Homo sapiens cDNA clone IMAGE:9051982, containing frame-shift errors.
AB070706 - Homo sapiens RPK118 mRNA for RSK-like protein, complete cds.
EF491805 - Homo sapiens clone RPS6KC1 mRNA, partial sequence; alternatively spliced.

-  Other Names for This Gene
  Alternate Gene Symbols: EF491820
UCSC ID: uc009xdi.1
RefSeq Accession: NM_012424

-  Gene Model Information
category: nearCoding nonsense-mediated-decay: no RNA accession: EF491820.1
exon count: 2CDS single in 3' UTR: no RNA size: 181
ORF size: 0CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 258.00frame shift in genome: no % Coverage: 100.00
has start codon: no stop codon in genome: no # of Alignments: 1
has end codon: no retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.