Human Gene RPS6KC1 (uc009xdi.1) Description and Page Index
Description: Homo sapiens ribosomal protein S6 kinase, 52kDa, polypeptide 1 (RPS6KC1), transcript variant 1, mRNA. RefSeq Summary (NM_012424): Sphingosine kinase catalyzes the formation of sphingosine 1 phosphate, a lipid cellular messenger. The protein encoded by this gene can bind to sphingosine kinase and to phosphatidylinositol 3-phosphate, suggesting a role in sphingosine 1 phophate signaling. The encoded protein can also bind to peroxiredoxin-3 and may help transport it to mitochondria. [provided by RefSeq, Mar 2017]. Transcript (Including UTRs) Position: hg19 chr1:213,234,724-213,244,383 Size: 9,660 Total Exon Count: 2 Strand: +
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Descriptions from all associated GenBank mRNAs
AK122989 - Homo sapiens cDNA FLJ16747 fis, clone FCBBF3008159, highly similar to Ribosomal protein S6 kinase delta-1 (EC 220.127.116.11). AK299298 - Homo sapiens cDNA FLJ50840 complete cds, highly similar to Ribosomal protein S6 kinase delta-1 (EC 18.104.22.168). AF477978 - Homo sapiens RSK-like protein (RPK118) mRNA, complete cds. BC104769 - Homo sapiens ribosomal protein S6 kinase, 52kDa, polypeptide 1, mRNA (cDNA clone MGC:132429 IMAGE:8143772), complete cds. BC143449 - Homo sapiens cDNA clone IMAGE:9051957, with apparent retained intron. BC143473 - Homo sapiens cDNA clone IMAGE:9051981. BC143474 - Homo sapiens cDNA clone IMAGE:9051982, containing frame-shift errors. AB070706 - Homo sapiens RPK118 mRNA for RSK-like protein, complete cds. EF491805 - Homo sapiens clone RPS6KC1 mRNA, partial sequence; alternatively spliced.