Human Gene MORF4L1 (uc010blj.2) Description and Page Index
Description: Homo sapiens mortality factor 4 like 1 (MORF4L1), transcript variant 1, mRNA.
Transcript (Including UTRs)
Position: hg19 chr15:79,165,123-79,185,360 Size: 20,238 Total Exon Count: 7 Strand: +
Position: hg19 chr15:79,165,360-79,184,664 Size: 19,305 Coding Exon Count: 7
Data last updated: 2013-06-15
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
DESCRIPTION: SubName: Full=Mortality factor 4-like protein 1;
CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
Genetic Association Studies of Complex Diseases and Disorders
Genetic Association Database (archive):
MORF4L1 CDC HuGE Published Literature:
MORF4L1 Positive Disease Associations: Heart Rate
Heart Rate , , .
MalaCards Disease Associations
Comparative Toxicogenomics Database (CTD)
Common Gene Haplotype Alleles
Press "+" in the title bar above to open this section.
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
Press "+" in the title bar above to open this section.
mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR000953 - Chromo_domain/shadow
IPR016197 - Chromodomain-like
IPR017398 - EAF3/MRG15
IPR008676 - MRG
IPR026541 - MRG_dom
IPR025995 - Tudor-knot
Pfam Domains: PF05712 - MRG
PF11717 - RNA binding activity-knot of a chromodomain
ModBase Predicted Comparative 3D Structure on H0YLJ3
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse Rat Zebrafish D. melanogaster C. elegans S. cerevisiae
No ortholog No ortholog No ortholog No ortholog No ortholog No ortholog
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
AK095823 - Homo sapiens cDNA FLJ38504 fis, clone HCHON2000156, highly similar to Mortality factor 4-like protein 1. AK098485 - Homo sapiens cDNA FLJ25619 fis, clone STM02419, highly similar to TRANSCRIPTION FACTOR-LIKE PROTEIN MORF4. AF218011 - Homo sapiens clone PP368 unknown mRNA. AF100615 - Homo sapiens chromosome 15 MRG15 protein (MRG15) mRNA, complete cds. AY148481 - Homo sapiens putative transcription factor MRG15-2 (MRG15) mRNA, complete cds; alternatively spliced. AK296650 - Homo sapiens cDNA FLJ50561 complete cds, highly similar to Mortality factor 4-like protein 1. BC002936 - Homo sapiens mortality factor 4 like 1, mRNA (cDNA clone MGC:10631 IMAGE:3955120), complete cds. BC022845 - Homo sapiens mortality factor 4 like 1, mRNA (cDNA clone MGC:1262 IMAGE:2988803), complete cds. AK310702 - Homo sapiens cDNA, FLJ17744. BC141840 - Homo sapiens mortality factor 4 like 1, mRNA (cDNA clone MGC:166970 IMAGE:8860303), complete cds. AF070664 - Homo sapiens HSPC008 mRNA, complete cds. AF167173 - Homo sapiens chromosome X MSL3-1 protein mRNA, complete cds. AK310592 - Homo sapiens cDNA, FLJ17634. AL137697 - Homo sapiens mRNA; cDNA DKFZp566F194 (from clone DKFZp566F194). AF109188 - Homo sapiens FWP006 mRNA, complete cds. AF161546 - Homo sapiens HSPC061 mRNA, complete cds. AK300789 - Homo sapiens cDNA FLJ50694 complete cds, highly similar to Mortality factor 4-like protein 1. BC067826 - Homo sapiens mortality factor 4 like 1, mRNA (cDNA clone MGC:87361 IMAGE:4824022), complete cds. CU692730 - Synthetic construct Homo sapiens gateway clone IMAGE:100018923 5' read MORF4L1 mRNA. AB385578 - Synthetic construct DNA, clone: pF1KB9446, Homo sapiens MORF4L1 gene for mortality factor 4-like protein 1, complete cds, without stop codon, in Flexi system. DQ892602 - Synthetic construct clone IMAGE:100005232; FLH188135.01X; RZPDo839G10150D mortality factor 4 like 1 (MORF4L1) gene, encodes complete protein. DQ895837 - Synthetic construct Homo sapiens clone IMAGE:100010297; FLH188131.01L; RZPDo839G10149D mortality factor 4 like 1 (MORF4L1) gene, encodes complete protein. KJ893172 - Synthetic construct Homo sapiens clone ccsbBroadEn_02566 MORF4L1 gene, encodes complete protein. AK310181 - Homo sapiens cDNA, FLJ17223. JD024428 - Sequence 5452 from Patent EP1572962. JD029863 - Sequence 10887 from Patent EP1572962. JD025067 - Sequence 6091 from Patent EP1572962. JD047852 - Sequence 28876 from Patent EP1572962. JD034132 - Sequence 15156 from Patent EP1572962. JD485891 - Sequence 466915 from Patent EP1572962. JD215540 - Sequence 196564 from Patent EP1572962. JD292630 - Sequence 273654 from Patent EP1572962. AF131847 - Homo sapiens clone 24896 mRNA sequence, partial cds. KJ904665 - Synthetic construct Homo sapiens clone ccsbBroadEn_14059 MORF4 gene, encodes complete protein. KJ906062 - Synthetic construct Homo sapiens clone ccsbBroadEn_15732 MORF4L1 gene, encodes complete protein. BC121092 - Homo sapiens mortality factor 4 like 1, mRNA (cDNA clone MGC:150374 IMAGE:40119977), complete cds. BC121093 - Homo sapiens mortality factor 4 like 1, mRNA (cDNA clone MGC:150375 IMAGE:40119978), complete cds.
Other Names for This Gene
Alternate Gene Symbols: AK310702, H0YLJ3, H0YLJ3_HUMAN, uc010blj.1 UCSC ID: uc010blj.2 RefSeq Accession: NM_006791
Gene Model Information
7 CDS single in 3' UTR:
468 CDS single in intron:
Alignment % ID:
1130.00 frame shift in genome:
has start codon:
stop codon in genome:
# of Alignments:
has end codon:
# AT/AC introns
end bleed into intron:
705 # strange splices:
for a detailed description of the fields of the table above.
Methods, Credits, and Use Restrictions
for details on how this gene model was made and data restrictions if any.