Human Gene MTFP1 (uc010gvy.1) Description and Page Index
Description: Homo sapiens mitochondrial fission process 1 (MTFP1), nuclear gene encoding mitochondrial protein, transcript variant 2, mRNA. RefSeq Summary (NM_001003704): MTP18 is a mitochondrial protein and downstream target of the phosphatidylinositol 3-kinase (see PIK3CA, MIM 171834) signaling pathway that plays a role in cell viability and mitochondrial dynamics (Tondera et al., 2004 [PubMed 15155745]).[supplied by OMIM, Mar 2008]. Transcript (Including UTRs) Position: hg19 chr22:30,805,415-30,825,041 Size: 19,627 Total Exon Count: 3 Strand: + Coding Region Position: hg19 chr22:30,805,424-30,824,717 Size: 19,294 Coding Exon Count: 3
ID:H7C1K3_HUMAN DESCRIPTION: SubName: Full=Uncharacterized protein; Flags: Fragment; SIMILARITY: Contains 1 CRAL-TRIO domain. CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on H7C1K3
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.