Human Gene ECM2 (uc010mqz.2) Description and Page Index
  Description: Homo sapiens extracellular matrix protein 2, female organ and adipocyte specific (ECM2), transcript variant 2, mRNA.
RefSeq Summary (NM_001197295): ECM2 encodes extracellular matrix protein 2, so named because it shares extensive similarity with known extracelluar matrix proteins. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010].
Transcript (Including UTRs)
   Position: hg19 chr9:95,257,594-95,268,731 Size: 11,138 Total Exon Count: 5 Strand: -
Coding Region
   Position: hg19 chr9:95,258,597-95,263,205 Size: 4,609 Coding Exon Count: 2 

Page IndexSequence and LinksGenetic AssociationsCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated: 2013-06-15

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr9:95,257,594-95,268,731)mRNA (may differ from genome)Protein (121 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
BioGPSCGAPEnsemblExonPrimerGeneCardsH-INV
HGNCLynxMGIPubMedStanford SOURCETreefam
Wikipedia

-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database (archive): ECM2
CDC HuGE Published Literature: ECM2
Positive Disease Associations: Breath Tests , Inflammation
Related Studies:
  1. Breath Tests
    , , . [PubMed 0]
  2. Inflammation
    , , . [PubMed 0]

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
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-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 29.20 RPKM in Artery - Coronary
Total median expression: 293.46 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -118.43535-0.221 Picture PostScript Text
3' UTR -201.471003-0.201 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Descriptions from all associated GenBank mRNAs
  BX537976 - Homo sapiens mRNA; cDNA DKFZp686O0186 (from clone DKFZp686O0186); complete cds.
AB011792 - Homo sapiens mRNA for extracellular matrix protein, complete cds.
AK303922 - Homo sapiens cDNA FLJ51183 complete cds, highly similar to Extracellular matrix protein 2 precursor.
AK298278 - Homo sapiens cDNA FLJ51022 complete cds, highly similar to Extracellular matrix protein 2 precursor.
AK296458 - Homo sapiens cDNA FLJ51676 complete cds, highly similar to Extracellular matrix protein 2 precursor.
AK312820 - Homo sapiens cDNA, FLJ93257, Homo sapiens extracellular matrix protein 2, female organ andadipocyte specific (ECM2), mRNA.
AB527312 - Synthetic construct DNA, clone: pF1KE0009, Homo sapiens ECM2 gene for extracellular matrix protein 2, female organ and adipocyte specific, without stop codon, in Flexi system.
AM393123 - Synthetic construct Homo sapiens clone IMAGE:100001929 for hypothetical protein (ECM2 gene).
JD545746 - Sequence 526770 from Patent EP1572962.
AK308485 - Homo sapiens cDNA, FLJ98526.
BC105958 - Homo sapiens extracellular matrix protein 2, female organ and adipocyte specific, mRNA (cDNA clone MGC:126355 IMAGE:40035034), complete cds.
BC107493 - Homo sapiens extracellular matrix protein 2, female organ and adipocyte specific, mRNA (cDNA clone MGC:126356 IMAGE:40035036), complete cds.
JD313548 - Sequence 294572 from Patent EP1572962.
JD341132 - Sequence 322156 from Patent EP1572962.
JD434754 - Sequence 415778 from Patent EP1572962.
JD038130 - Sequence 19154 from Patent EP1572962.
JD486688 - Sequence 467712 from Patent EP1572962.
JD284054 - Sequence 265078 from Patent EP1572962.
JD291353 - Sequence 272377 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: AK308485
UCSC ID: uc010mqz.2
RefSeq Accession: NM_001197295

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: AK308485.1
exon count: 5CDS single in 3' UTR: no RNA size: 1475
ORF size: 366CDS single in intron: no Alignment % ID: 99.93
txCdsPredict score: 840.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.