Human Gene MIR4505 (uc021rwi.1) Description and Page Index
  Description: Homo sapiens microRNA 4505 (MIR4505), microRNA.
RefSeq Summary (NR_039727): microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]. Sequence Note: This record represents a predicted microRNA stem-loop as defined by miRBase. Some sequence at the 5' and 3' ends may not be included in the intermediate precursor miRNA produced by Drosha cleavage. ##Evidence-Data-START## Transcript is intronless :: LM611335.1 [ECO:0000345] ##Evidence-Data-END##
Transcript (Including UTRs)
   Position: hg19 chr14:74,225,450-74,225,522 Size: 73 Total Exon Count: 1 Strand: +


Page IndexSequence and LinksRNA-Seq ExpressionMicroarray ExpressionOther SpeciesmRNA Descriptions
Other NamesModel InformationMethods
Data last updated: 2013-06-15

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr14:74,225,450-74,225,522)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSEnsembl
Entrez GeneExonPrimerHGNCLynxPubMedStanford SOURCE

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 0.00 RPKM in Adipose - Subcutaneous
Total median expression: 0.00 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  HZ409391 - JP 2015528002-A/1988: CHIRAL CONTROL.
HZ459506 - WO 2015182781-A/209: Kit or device and method for detecting pancreatic cancer.
HZ460813 - WO 2015190584-A/310: Kit or device and method for detecting prostate cancer.
HZ461547 - WO 2015190586-A/360: Kit and method for detecting colon cancer.
HZ462345 - WO 2015190591-A/500: Kit and method for detecting breast cancer.
LG052725 - KR 1020150036642-A/1991: CHIRAL CONTROL.
LY480946 - KR 1020170010856-A/209: PANCREATIC CANCER DETECTION KIT, DEVICE, AND DETECTION METHOD.
LY497190 - KR 1020170016485-A/360: COLORECTAL CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY499348 - KR 1020170018412-A/500: BREAST CANCER DETECTION KIT OR DEVICE, AND METHOD FOR DETECTING BREAST CANCER.
LY500686 - KR 1020170016490-A/310: PROSTATE CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LZ238801 - WO 2017171048-A/462: Kit, device and method for detecting early pancreatic cancer or precancerous lesion of pancreas.
MS869605 - Sequence 310 from Patent EP3156483.
MS880663 - Sequence 500 from Patent EP3156498.
MS884377 - Sequence 360 from Patent EP3156499.
HZ459603 - WO 2015182781-A/306: Kit or device and method for detecting pancreatic cancer.
HZ461013 - WO 2015190584-A/510: Kit or device and method for detecting prostate cancer.
HZ461755 - WO 2015190586-A/568: Kit and method for detecting colon cancer.
HZ462636 - WO 2015190591-A/791: Kit and method for detecting breast cancer.
LY481043 - KR 1020170010856-A/306: PANCREATIC CANCER DETECTION KIT, DEVICE, AND DETECTION METHOD.
LY497398 - KR 1020170016485-A/568: COLORECTAL CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY499639 - KR 1020170018412-A/791: BREAST CANCER DETECTION KIT OR DEVICE, AND METHOD FOR DETECTING BREAST CANCER.
LY500886 - KR 1020170016490-A/510: PROSTATE CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LZ239086 - WO 2017171048-A/747: Kit, device and method for detecting early pancreatic cancer or precancerous lesion of pancreas.
MS869805 - Sequence 510 from Patent EP3156483.
MS880954 - Sequence 791 from Patent EP3156498.
MS884585 - Sequence 568 from Patent EP3156499.
MA806111 - WO 2018199275-A/371: Kit, device and method for detection of ovary tumor.
MA806384 - WO 2018199275-A/644: Kit, device and method for detection of ovary tumor.
MA822578 - WO 2019004436-A/391: Kit, device, and method for detection of lung cancer.
MA822915 - WO 2019004436-A/728: Kit, device, and method for detection of lung cancer.
LY616565 - KR 1020180129785-A/462: KIT OR DEVICE FOR DETECTING EARLY STAGE PANCREATIC CANCER OR PANCREATIC CANCER PRECURSOR LESIONS AND DETECTION METHOD THEREFOR.
LY616850 - KR 1020180129785-A/747: KIT OR DEVICE FOR DETECTING EARLY STAGE PANCREATIC CANCER OR PANCREATIC CANCER PRECURSOR LESIONS AND DETECTION METHOD THEREFOR.
MB407320 - WO 2019159884-A/810: Kit, device, and method for detection of dementia.

-  Other Names for This Gene
  Alternate Gene Symbols: NR_039727
UCSC ID: uc021rwi.1
RefSeq Accession: NR_039727

-  Gene Model Information
 
category: noncoding nonsense-mediated-decay: no RNA accession: NR_039727.1
exon count: 1CDS single in 3' UTR: no RNA size: 73
ORF size: 0CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 80.00frame shift in genome: no % Coverage: 100.00
has start codon: no stop codon in genome: no # of Alignments: 1
has end codon: no retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.